6th Cancer Cachexia Hybrid Conference 
August 27-29, 2021
Gainesville, Florida and Online

Preliminary Program
Bridging Molecular Advances to Clinical Care

Presentations will be recorded. Times correspond to US East Coast Time Zone.

Updated: June 19, 2021

Friday, August 27, 2021

7:30 am Registration
Clinical Advances in Cancer Cachexia

Session A: Outcome Measures for Cancer Cachexia

Richard Dunne, MD – University of Rochester, USA

8:20 am Introductory Remarks
8:30 am David Currow, MD
University of Technology Sydney, Australia
“What have we learnt from clinical trials in cancer cachexia?”
9:00 am TBA
9:30 am Jorge Nieva, MD
University of Southern California, USA
“Karnofsky revisited – Measuring performance status in the digital age”
10:00 am Coffee Break

Session B: Clinical Trial Results

10:30 am Marie Fallon, MD
University of Edinburgh, UK
“Phenotyping of patients in clinical trials of cancer cachexia”
11:00 am Tora Solheim, MD
St. Olavs Hospital, Trondheim University Hospital, Norway
“Why do we need a complex intervention in cancer cachexia?”
11:30 am Stein Kaasa, MD
Norwegian University of Science and Technology
“Cancer cachexia classification anno 2022: A common system for research and clinical practice?”
  Selected Short Talks
12:00 pm Short Talk 1 (selected from abstracts)
12:15 pm Short Talk 2 (selected from abstracts)
12:30 pm Lunch
Grab and go lunches will be provided

Session C: Conversations with Caregivers and Patients

Thomas R. Jagoe, MD – McGill University, Canada
Martin Kochanczyk, PhD – Pattern Bioscience, USA

1:30–2:30 pm Program for Caregivers and Patients
2:30 pm Poster Set Up
Session 1
Introductory Remarks and Keynote Address

Denis Guttridge, PhD – Medical University of South Carolina, USA
Teresa Zimmers, PhD – Indiana University, USA

3:45 pm Introductions to the 6th Cancer Cachexia Conference
Denis Guttridge, PhD
Medical University of South Carolina, USA & President of the Cancer Cachexia Society
4:00 pm Kenneth C.H. Fearon Keynote Lectureship
Bette J Caan, PhD
Kaiser Permanente, USA
"Muscle wasting in non-metastatic cancer: Advances in our understanding, assessment and treatment"
  Cutting Edge Science in Cancer Cachexia
Six trainee speakers chosen from selected abstracts (Virtual Platform)
5:00 pm Speaker 1 – TBA
5:05 pm Speaker 2 – TBA
5:10 pm Speaker 3 – TBA
5:15 pm Speaker 4 – TBA
5:20 pm Speaker 5 – TBA
5:25 pm Speaker 6 – TBA
5:30-7:30 pm Welcoming Reception

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Saturday, August 28, 2021

6:30-8:30 am Breakfast
Session 2
Metabolic Dysfunction in Cancer Cachexia

Emidio Pistilli, PhD – West Virginia University, USA
Erin Talbert, PhD – University of Iowa, USA

8:30 am Pankaj K. Singh, PhD
University of Nebraska Medical Center, USA
"Molecular regulation of oxidative damage in skeletal muscle in pancreatic cancer"
9:00 am Stephan Herzig, PhD
Helmholtz Diabetes and Cancer Center, Germany
"Organ-specific metabolic programs in cancer cachexia"
  Selected Short Talks
9:30 am Short Talk 3 (selected from abstracts)
9:45 am Short Talk 4 (selected from abstracts)
10:30 am Coffee Break
Session 3
Mechanisms of Skeletal Muscle Wasting: Myofiber

Gabriela Salim de Castro, PhD – University of São Paulo, Brazil
Derek Hall, PhD – University of Ottawa, Canada

11:00 am Paul Gregorevic, PhD
University of Melbourne, Australia
“Exploring and targeting new mechanisms implicated in muscle wasting associated with cancer cachexia”
11:30 am David Glass, MD
Regeneron, USA
“Cancer cachexia lessons applied to understanding Covid-19”
12:00 pm Andrew Judge, PhD
University of Florida, USA
“Mechanisms of cachexia initiation”
12:30 pm Lunch
1:30-4:00 pm Poster Viewing
Session 4
Nutrition Imbalance and Strategies in Cancer Cachexia

Rishi Jain, MD – Fox Chase Cancer Center, USA

4:00 pm TBA
4:30 pm TBA
  Selected Short Talks
5:00 pm Short Talk 5
(selected from abstracts)
5:15 pm Short Talk 6
(selected from abstracts)
5:30 pm End of program day
5:45 pm Cancer Cachexia Society Members Business Meeting

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Sunday, August 29, 2021

6:30-8:30 am Breakfast
Session 5
Biological Variables in Cancer Cachexia

Andrea Bonetto, PhD – Indiana University, USA
Sarah Judge, PhD – University of Florida, USA

8:30 am Vickie Baracos, PhD
University of Alberta, Canada
9:00 am James Carson, PhD
University of Tennessee Health Science Center, USA
“Understanding female systemic and skeletal muscle metabolic dysfunction with cancer cachexia and chemotherapy in mice”
  Selected Short Talks
9:30 am Short Talk 7 (selected from abstracts)
9:45 am Short Talk 8 (selected from abstracts)
10:00 am Coffee Break
Session 6
Next Generation Researchers in Cancer Cachexia

Melissa Puppa, PhD – The University of Memphis, USA
Marcus Concalves, MD, PhD – Weill Cornell Medical College, USA

To promote upcoming and young faculty researchers: Speakers chosen from submitted applications.

10:30 am Speaker 1 – TBA
10:45 am Speaker 2 – TBA
11:00 am Speaker 3 – TBA
11:15 am Speaker 4 – TBA
11:30 am Speaker 5 – TBA
11:45 am Speaker 6 – TBA
12:00 pm Lunch
Session 7
Mechanisms of Muscle Wasting: Muscle Microenvironment

Fabio Penna, PhD – University of Torino, Italy
Roberta Sartori, PhD – University of Padova, Italy

1:30 pm Michael Rudnicki, PhD
University of Ottawa, Canada
"Molecular regulation of stem cell function"
2:00 pm Denis Guttridge, PhD
Medical University of South Carolina, USA
“The interplay between the inflammatory cascade and muscle atrophy in cancer cachexia”
2:30 pm Jerome Feige, PhD
Nestle, Switzerland
"Crosstalk in the muscle stem cell niche during aging and cachexia"
3:00 pm Coffee Break
Session 8
Therapy-Induced Muscle Dysfunction and Wasting

Ashley Smuder, PhD – University of Florida, USA

3:30 pm Andrea Bonetto, PhD
Indiana University, USA
"Mechanisms of chemotherapy-induced musculoskeletal complications"
4:00 pm Chris Coss, PhD
Ohio State University, USA
"Modeling clearance of immune checkpoint inhibitors as a potential for drug resistance in murine models of cancer cachexia"
  Selected Short Talks
4:30 pm Short Talk 9 (selected from abstracts)
4:45 pm Short Talk 10 (selected from abstracts)
5:00 pm Closing Remarks

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